篇名

可望改善老年失智的智能新藥【醫事綜探】   試閱

並列篇名

New Drug Raises Hopes of Reversing Memory Loss in Old Age

作者
中文摘要

如何避免在數位時代失去記憶─市場上沒有藥物可以改善老年人的失智、抑鬱症、精神分裂症等精神疾病。但多倫多研究人員認為,他們的藥物可以透過針對學習和記憶中的特定細胞,並使細胞恢復活力來逆轉失去的記憶。藥物在大腦中帶來的變化表明,其可預防阿茲海默症初期的記憶喪失,並可能延緩其發病。2019年2月相關研究人員在華盛頓特區舉行的美國科學促進會年會上發表了一項關於該藥物的專利,科學家們希望在人類身上測試這種藥物,預計首次試驗將在憂鬱症患者身上進行。

英文摘要

Avoiding losing your memory in the digital age ─ There are no medicines on the market that improve the sort of memory loss seen in old age and psychiatric disorders such as depression and schizophrenia. But the Toronto researchers believe their new drug can reverse failing memories by targeting specific cells involved in learning and memory, and rejuvenating them. The changes the drug brings about in the brain suggest it could prevent memory loss at the beginning of Alzheimer’s and potentially delay its onset. The researchers submitted a patent on the drug on Wednesday before a talk at the American Association for the Advancement of Science annual meeting in Washington DC. Scientists now hope to test the drug in humans, with the first trials expected to be in people with depression.

起訖頁

165-174

出版單位
DOI

10.3966/241553062020020040013  複製DOI  DOI查詢

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